| MW: |
~85kDa |
| SOURCE/HOST: |
Produced in HEK 293 cells. Human EBI3 (aa 21-229) linked to human IL-12A (aa 23-219) via the linker GGGSGGGSGGGSGGGS is fused at the C-terminus to the Fc portion of human IgG1 and a FLAG®-tag. |
| CONCENTRATION: |
0.1mg/ml after reconstitution. |
| PURITY: |
≥95% (SDS-PAGE) |
| FORMULATION: |
Lyophilized. Contains PBS. |
| ENDOTOXIN CONTENT: |
<0.1EU/µg purified protein (LAL test; Lonza). |
| RECONSTITUTION: |
Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein. |
| ACTIVITY: |
Binds to human IL-12 Rβ2. |
| BIOLOGICAL ACTIVITY: |
Inhibits human mononuclear cell proliferation. |
| SHIPPING: |
SHIPPED ON BLUE ICE |
| SHORT TERM STORAGE: |
+4°C |
| LONG TERM STORAGE: |
-20°C |
| USE/STABILITY: |
Stable for at least 6 months after receipt when stored at -20°C. |
| HANDLING: |
Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C. |