ALEXIS Biochemicals: FHL-1 (human) (recombinant)

ALX-201-297

Revised 28-Oct-08

FHL-1 (human) (recombinant)
SYNONYMS	Factor H-like Protein 1 (human) (recombinant) Reconectin (human) (recombinant)
PRODUCT LINE	Immunology
PRODUCT CATEGORY	Complement Factors / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-201-297-1		1 Vial	260.00 USD

Product Specification

SOURCE/HOST:	Produced in Pichia pastoris.
QUANTITY:	250µl (sufficient for at least 25 Western blot analyses under standard conditions).
CONCENTRATION:	100µg/ml
FORMULATION:	Liquid. In PBS, pH 7.4.
SPECIFICITY:	Interacts with complement component C3b.
BIOLOGICAL ACTIVITY:	Cofactor for Factor I in proteolytic cleavage of C3b to iC3b.
APPLICATION:	Protein/protein interaction studies (ligand blots, biacore assays, flow cytometry or ELISA).
SHIPPING:	SHIPPED ON DRY ICE
LONG TERM STORAGE:	-80°C
HANDLING:	Avoid freeze/thaw cycles.

Product Specific Literature References

Defective complement control of factor H (Y402H) and FHL-1 in age-related macular degeneration: C. Skerka, et al.; Mol. Immunol. 44, 3398 (2007) Abstract
Human pathogenic Borrelia spielmanii sp. nov. resists complement-mediated killing by direct binding of immune regulators factor H and factor H-like protein 1: P. Herzberger, et al.; Infect. Immun. 75, 4817 (2007) Abstract; Full Text

General Information

Splicing variant of complement factor H (CFH) with seven SCR domains.
BACKGROUND/TECHNICAL INFORMATION	Swiss-Prot link P08603-2: FHL-1 (human)

Further Categories Containing This Product:

Recombinant Proteins / Fusion Proteins

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