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ALX-805-008 Revised 13-Jun-06
Monoclonal Antibody to Fas (human) (SM1/1)
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SYNONYMS anti-CD95 (human) MAb (SM1/1)
anti-APO-1 (human) MAb (SM1/1)
anti-TNFRSF 6 (human) MAb (SM1/1)
PRODUCT LINE Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY Fas Antibodies
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-805-008-C100   100 µg 259.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: SM1/1
ISOTYPE: Mouse IgG2a
CONCENTRATION: 1mg/ml
PURITY: >95% (SDS-PAGE)
FORMULATION: Liquid. In PBS.
IMMUNOGEN: Human Fas (CD95; APO-1).
SPECIFICITY: Recognizes human Fas.
APPLICATION: Flow Cytometry
Functional Application:
Induces apoptosis at 100-500 ng/ml in Jurkat cells and SKW6.4 cells if secondary cross-linking with anti-mouse IgG is used. Induces apoptosis in human Fas-transfectants without crosslinking. 
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Specific Literature References
The antitumor ether lipid ET-18-OCH(3) induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells: C. Gajate & F. Mollinedo; Blood 98, 3860 (2001) Abstract; Full Text
Further Categories Containing This Product:
Monoclonal AntibodiesCD Antibodies
 
 

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