ALEXIS Biochemicals: Monoclonal Antibody to JAM-C (human) (Gi11)

ALX-803-306

Revised 21-Apr-06

Monoclonal Antibody to JAM-C (human) (Gi11)
SYNONYMS	anti-Junctional Adhesion Molecule C (human) MAb (Gi11) anti-JAM-2 (human) (Gi11) anti-JAM-3 (human) (Gi11)
PRODUCT LINE	Cytoskeleton
PRODUCT CATEGORY	Immunoglobulin Superfamily Cell Adhesion Molecules [IgSF CAMs] / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-803-306-C050		50 µg	120.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human
CLONE:	Gi11
ISOTYPE:	Mouse IgG1
CONCENTRATION:	1mg/ml
PURITY:	≥95% (SDS-PAGE)
FORMULATION:	Liquid. In buffer containing 0.09% sodium azide.
IMMUNOGEN:	Human platelets.
SPECIFICITY:	Recognizes human JAM-C (Junctional Adhesion Molecule C).
APPLICATION:	ELISA (1:500) Flow Cytometry (1:40) Immunocytochemistry (1:100) Immunoprecipitation (1:20) Western Blot (1:200)
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
HANDLING:	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.

Product Specific Literature References

The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1: S. Santoso, et al.; J. Exp. Med. 196, 679 (2002) Abstract; Full Text
The junctional adhesion molecule-C promotes neutrophil transendothelial migration in vitro and in vivo: T. Chavakis, et al.; J. Biol. Chem. 279, 55602 (2004) Abstract; Full Text
The homophilic binding of junctional adhesion molecule-C mediates tumor cell-endothelial cell interactions: S. Santoso, et al.; J. Biol. Chem. 280, 36326 (2005) Abstract; Full Text
The role of junctional adhesion molecule-C (JAM-C) in oxidized LDL-mediated leukocyte recruitment: T. Keiper, et al.; FASEB J. 19, 2078 (2005) Abstract

Further Categories Containing This Product:

Tight Junctions / Related Products • Monoclonal Antibodies

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